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Antibodies against High Mobility Group Box protein-1 (HMGB1) versus other anti-nuclear antibody fine-specificities and disease activity in systemic lupus erythematosus
INTRODUCTION: The non-histone nuclear protein high mobility group box protein-1 (HMGB1) is typically associated with nucleosomes, but may shuttle between the nucleus and the cytoplasm, and under some conditions also be released extracellularly and participate in systemic inflammation. Monoclonal HMG...
Autores principales: | Wirestam, Lina, Schierbeck, Hanna, Skogh, Thomas, Gunnarsson, Iva, Ottosson, Lars, Erlandsson-Harris, Helena, Wetterö, Jonas, Sjöwall, Christopher |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657231/ https://www.ncbi.nlm.nih.gov/pubmed/26596890 http://dx.doi.org/10.1186/s13075-015-0856-2 |
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