Cargando…

Molecular interplay between T-Antigen and splicing factor, arginine/serine-rich 1 (SRSF1) controls JC virus gene expression in glial cells

BACKGROUND: Human polyomavirus JCV is the etiologic agent of progressive multifocal leukoencephalopathy (PML), a fatal demyelinating disease characterized by lytic infection of glial cells in the central nervous system. PML is seen primarily in immunosuppressed patients and is mainly classified as a...

Descripción completa

Detalles Bibliográficos
Autores principales: Craigie, Michael, Regan, Patrick, Otalora, Yolanda-Lopez, Sariyer, Ilker Kudret
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657255/
https://www.ncbi.nlm.nih.gov/pubmed/26596376
http://dx.doi.org/10.1186/s12985-015-0426-x

Ejemplares similares