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Inflammation and neuronal death in the motor cortex of the wobbler mouse, an ALS animal model

BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder of the upper and lower motor neurons, characterized by rapid progressive weakness, muscle atrophy, dysarthria, dysphagia, and dyspnea. Whereas the exact cause of ALS remains uncertain, the wobbler mouse (phenotype...

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Detalles Bibliográficos
Autores principales:	Dahlke, Carolin, Saberi, Darius, Ott, Bastian, Brand-Saberi, Beate, Schmitt-John, Thomas, Theiss, Carsten
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657283/ https://www.ncbi.nlm.nih.gov/pubmed/26597538 http://dx.doi.org/10.1186/s12974-015-0435-0

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