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Intravitreal AAV2.COMP-Ang1 Prevents Neurovascular Degeneration in a Murine Model of Diabetic Retinopathy
Diabetic retinopathy (DR) is the leading cause of blindness in the working-age population in the U.S. The vision-threatening processes of neuroglial and vascular dysfunction in DR occur in concert, driven by hyperglycemia and propelled by a pathway of inflammation, ischemia, vasodegeneration, and br...
Autores principales: | Cahoon, Judd M., Rai, Ruju R., Carroll, Lara S., Uehara, Hironori, Zhang, Xiaohui, O’Neil, Christina L., Medina, Reinhold J., Das, Subtrata K., Muddana, Santosh K., Olson, Paul R., Nielson, Spencer, Walker, Kortnie, Flood, Maggie M., Messenger, Wyatt B., Archer, Bonnie J., Barabas, Peter, Krizaj, David, Gibson, Christopher C., Li, Dean Y., Koh, Gou Y., Gao, Guangping, Stitt, Alan W., Ambati, Balamurali K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657578/ https://www.ncbi.nlm.nih.gov/pubmed/26340930 http://dx.doi.org/10.2337/db14-1030 |
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