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Tacrolimus Induces Insulin Resistance and Increases the Glucose Absorption in the Jejunum: A Potential Mechanism of the Diabetogenic Effects

BACKGROUND: The use of the immunosuppressive drug tacrolimus (TAC) is related to new onset diabetes after transplantation. Herein, we examined the effect of intraperitoneal administered TAC on intestinal glucose absorption in mice. METHODS: Animals received low, medium, or high dose TAC (0.5, 1, or...

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Detalles Bibliográficos
Autores principales:	Li, Zhiwei, Sun, Fei, Zhang, Yaohui, Chen, Hao, He, Ningning, Chen, Hui, Song, Penghong, Wang, Yan, Yan, Sheng, Zheng, Shusen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657894/ https://www.ncbi.nlm.nih.gov/pubmed/26599323 http://dx.doi.org/10.1371/journal.pone.0143405

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