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The Impact of Human Mobility on HIV Transmission in Kenya

Disease spreads as a result of people moving and coming in contact with each other. Thus the mobility patterns of individuals are crucial in understanding disease dynamics. Here we study the impact of human mobility on HIV transmission in different parts of Kenya. We build an SIR metapopulation mode...

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Detalles Bibliográficos
Autores principales: Isdory, Augustino, Mureithi, Eunice W., Sumpter, David J. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657931/
https://www.ncbi.nlm.nih.gov/pubmed/26599277
http://dx.doi.org/10.1371/journal.pone.0142805
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author Isdory, Augustino
Mureithi, Eunice W.
Sumpter, David J. T.
author_facet Isdory, Augustino
Mureithi, Eunice W.
Sumpter, David J. T.
author_sort Isdory, Augustino
collection PubMed
description Disease spreads as a result of people moving and coming in contact with each other. Thus the mobility patterns of individuals are crucial in understanding disease dynamics. Here we study the impact of human mobility on HIV transmission in different parts of Kenya. We build an SIR metapopulation model that incorporates the different regions within the country. We parameterise the model using census data, HIV data and mobile phone data adopted to track human mobility. We found that movement between different regions appears to have a relatively small overall effect on the total increase in HIV cases in Kenya. However, the most important consequence of movement patterns was transmission of the disease from high infection to low prevalence areas. Mobility slightly increases HIV incidence rates in regions with initially low HIV prevalences and slightly decreases incidences in regions with initially high HIV prevalence. We discuss how regional HIV models could be used in public-health planning. This paper is a first attempt to model spread of HIV using mobile phone data, and we also discuss limitations to the approach.
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spelling pubmed-46579312015-12-02 The Impact of Human Mobility on HIV Transmission in Kenya Isdory, Augustino Mureithi, Eunice W. Sumpter, David J. T. PLoS One Research Article Disease spreads as a result of people moving and coming in contact with each other. Thus the mobility patterns of individuals are crucial in understanding disease dynamics. Here we study the impact of human mobility on HIV transmission in different parts of Kenya. We build an SIR metapopulation model that incorporates the different regions within the country. We parameterise the model using census data, HIV data and mobile phone data adopted to track human mobility. We found that movement between different regions appears to have a relatively small overall effect on the total increase in HIV cases in Kenya. However, the most important consequence of movement patterns was transmission of the disease from high infection to low prevalence areas. Mobility slightly increases HIV incidence rates in regions with initially low HIV prevalences and slightly decreases incidences in regions with initially high HIV prevalence. We discuss how regional HIV models could be used in public-health planning. This paper is a first attempt to model spread of HIV using mobile phone data, and we also discuss limitations to the approach. Public Library of Science 2015-11-24 /pmc/articles/PMC4657931/ /pubmed/26599277 http://dx.doi.org/10.1371/journal.pone.0142805 Text en © 2015 Isdory et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Isdory, Augustino
Mureithi, Eunice W.
Sumpter, David J. T.
The Impact of Human Mobility on HIV Transmission in Kenya
title The Impact of Human Mobility on HIV Transmission in Kenya
title_full The Impact of Human Mobility on HIV Transmission in Kenya
title_fullStr The Impact of Human Mobility on HIV Transmission in Kenya
title_full_unstemmed The Impact of Human Mobility on HIV Transmission in Kenya
title_short The Impact of Human Mobility on HIV Transmission in Kenya
title_sort impact of human mobility on hiv transmission in kenya
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657931/
https://www.ncbi.nlm.nih.gov/pubmed/26599277
http://dx.doi.org/10.1371/journal.pone.0142805
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