A New Method to Quantify Ifosfamide Blood Levels Using Dried Blood Spots and UPLC-MS/MS in Paediatric Patients with Embryonic Solid Tumours

Ifosfamide blood concentrations are necessary to monitor its therapeutic response, avoiding any adverse effect. We developed and validated an analytical method by UPLC-MS/MS to quantify ifosfamide in dried blood spots (DBS). Blood samples were collected on Whatman 903® filter paper cards. Five 3 mm...

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Detalles Bibliográficos
Autores principales: Torres, Luz-María, Rivera-Espinosa, Liliana, Chávez-Pacheco, Juan L., Navas, Carlos F., Demetrio, Joel A., Alemón-Medina, Radamés, Trujillo, Francisca, Pérez, Martín, Zapata, Martha M., Cárdenas, Rocío, Salinas, Citlaltepetl, Aquino, Arnoldo, Velázquez-Cruz, Rafael, Castillejos, Manuel-de-Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657950/
https://www.ncbi.nlm.nih.gov/pubmed/26600181
http://dx.doi.org/10.1371/journal.pone.0143421

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