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Respiratory DC Use IFITM3 to Avoid Direct Viral Infection and Safeguard Virus-Specific CD8(+) T Cell Priming

Respiratory dendritic cells (DC) play a pivotal role in the initiation of adaptive immune responses to influenza virus. To do this, respiratory DCs must ferry viral antigen from the lung to the draining lymph node without becoming infected and perishing en route. We show that respiratory DCs up-regu...

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Detalles Bibliográficos
Autores principales:	Infusini, Giuseppe, Smith, Jeffrey M., Yuan, He, Pizzolla, Angela, Ng, Wy Ching, Londrigan, Sarah L., Haque, Ashraful, Reading, Patrick C., Villadangos, Jose A., Wakim, Linda M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657952/ https://www.ncbi.nlm.nih.gov/pubmed/26600246 http://dx.doi.org/10.1371/journal.pone.0143539

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