A Flexible, Efficient Binomial Mixed Model for Identifying Differential DNA Methylation in Bisulfite Sequencing Data

Identifying sources of variation in DNA methylation levels is important for understanding gene regulation. Recently, bisulfite sequencing has become a popular tool for investigating DNA methylation levels. However, modeling bisulfite sequencing data is complicated by dramatic variation in coverage a...

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Detalles Bibliográficos
Autores principales: Lea, Amanda J., Tung, Jenny, Zhou, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657956/
https://www.ncbi.nlm.nih.gov/pubmed/26599596
http://dx.doi.org/10.1371/journal.pgen.1005650

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657956/
https://www.ncbi.nlm.nih.gov/pubmed/26599596
http://dx.doi.org/10.1371/journal.pgen.1005650

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