Positive Allosteric Modulation of Kv Channels by Sevoflurane: Insights into the Structural Basis of Inhaled Anesthetic Action

Inhalational general anesthesia results from the poorly understood interactions of haloethers with multiple protein targets, which prominently includes ion channels in the nervous system. Previously, we reported that the commonly used inhaled anesthetic sevoflurane potentiates the activity of voltag...

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Detalles Bibliográficos
Autores principales: Liang, Qiansheng, Anderson, Warren D., Jones, Shelly T., Souza, Caio S., Hosoume, Juliana M., Treptow, Werner, Covarrubias, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657974/
https://www.ncbi.nlm.nih.gov/pubmed/26599217
http://dx.doi.org/10.1371/journal.pone.0143363

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