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Mutant SOD1 Increases APP Expression and Phosphorylation in Cellular and Animal Models of ALS
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease and it is the most common adult onset neurodegenerative disorder affecting motor neurons. There is currently no effective treatment for ALS and our understanding of the pathological mechanism is still far away from prevention a...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658003/ https://www.ncbi.nlm.nih.gov/pubmed/26600047 http://dx.doi.org/10.1371/journal.pone.0143420 |