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Mutant SOD1 Increases APP Expression and Phosphorylation in Cellular and Animal Models of ALS

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease and it is the most common adult onset neurodegenerative disorder affecting motor neurons. There is currently no effective treatment for ALS and our understanding of the pathological mechanism is still far away from prevention a...

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Detalles Bibliográficos
Autores principales: Rabinovich-Toidman, Polina, Rabinovich-Nikitin, Inna, Ezra, Assaf, Barbiro, Beka, Fogel, Hilla, Slutsky, Inna, Solomon, Beka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658003/
https://www.ncbi.nlm.nih.gov/pubmed/26600047
http://dx.doi.org/10.1371/journal.pone.0143420