A Novel MVA-Based Multiphasic Vaccine for Prevention or Treatment of Tuberculosis Induces Broad and Multifunctional Cell-Mediated Immunity in Mice and Primates

Bacille Calmette-Guérin (BCG) vaccination of new born babies can protect children against tuberculosis (TB), but fails to protect adults consistently against pulmonary TB underlying the urgent need to develop novel TB vaccines. Majority of first generation TB vaccine candidates have relied on a very...

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Detalles Bibliográficos
Autores principales: Leung-Theung-Long, Stéphane, Gouanvic, Marie, Coupet, Charles-Antoine, Ray, Aurélie, Tupin, Emmanuel, Silvestre, Nathalie, Marchand, Jean-Baptiste, Schmitt, Doris, Hoffmann, Chantal, Klein, Murielle, Seegren, Philip, Huaman, Maria C., Cristillo, Anthony D., Inchauspé, Geneviève
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658014/
https://www.ncbi.nlm.nih.gov/pubmed/26599077
http://dx.doi.org/10.1371/journal.pone.0143552

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