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High-Throughput Screening of Myometrial Calcium-Mobilization to Identify Modulators of Uterine Contractility
The uterine myometrium (UT-myo) is a therapeutic target for preterm labor, labor induction, and postpartum hemorrhage. Stimulation of intracellular Ca(2+)-release in UT-myo cells by oxytocin is a final pathway controlling myometrial contractions. The goal of this study was to develop a dual-addition...
Autores principales: | Herington, Jennifer L., Swale, Daniel R., Brown, Naoko, Shelton, Elaine L., Choi, Hyehun, Williams, Charles H., Hong, Charles C., Paria, Bibhash C., Denton, Jerod S., Reese, Jeff |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658040/ https://www.ncbi.nlm.nih.gov/pubmed/26600013 http://dx.doi.org/10.1371/journal.pone.0143243 |
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