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Association of Genetically Determined Aldehyde Dehydrogenase 2 Activity with Diabetic Complications in Relation to Alcohol Consumption in Japanese Patients with Type 2 Diabetes Mellitus: The Fukuoka Diabetes Registry
Aldehyde dehydrogenase 2 (ALDH2) detoxifies aldehyde produced during ethanol metabolism and oxidative stress. A genetic defect in this enzyme is common in East Asians and determines alcohol consumption behaviors. We investigated the impact of genetically determined ALDH2 activity on diabetic microva...
Autores principales: | Idewaki, Yasuhiro, Iwase, Masanori, Fujii, Hiroki, Ohkuma, Toshiaki, Ide, Hitoshi, Kaizu, Shinako, Jodai, Tamaki, Kikuchi, Yohei, Hirano, Atsushi, Nakamura, Udai, Kubo, Michiaki, Kitazono, Takanari |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658066/ https://www.ncbi.nlm.nih.gov/pubmed/26599441 http://dx.doi.org/10.1371/journal.pone.0143288 |
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