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Rhinovirus Load Is High despite Preserved Interferon-β Response in Cystic Fibrosis Bronchial Epithelial Cells

Lung disease in cystic fibrosis (CF) is often exacerbated following acute upper respiratory tract infections caused by the human rhinovirus (HRV). Pathophysiology of these exacerbations is presently unclear and may involve deficient innate antiviral or exaggerated inflammatory responses in CF airway...

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Detalles Bibliográficos
Autores principales: Dauletbaev, Nurlan, Das, Mithun, Cammisano, Maria, Chen, He, Singh, Sareen, Kooi, Cora, Leigh, Richard, Beaudoin, Trevor, Rousseau, Simon, Lands, Larry C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658124/
https://www.ncbi.nlm.nih.gov/pubmed/26599098
http://dx.doi.org/10.1371/journal.pone.0143129