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Using Blood Indexes to Predict Overweight Statuses: An Extreme Learning Machine-Based Approach

The number of the overweight people continues to rise across the world. Studies have shown that being overweight can increase health risks, such as high blood pressure, diabetes mellitus, coronary heart disease, and certain forms of cancer. Therefore, identifying the overweight status in people is c...

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Detalles Bibliográficos
Autores principales: Chen, Huiling, Yang, Bo, Liu, Dayou, Liu, Wenbin, Liu, Yanlong, Zhang, Xiuhua, Hu, Lufeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658146/
https://www.ncbi.nlm.nih.gov/pubmed/26600199
http://dx.doi.org/10.1371/journal.pone.0143003
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author Chen, Huiling
Yang, Bo
Liu, Dayou
Liu, Wenbin
Liu, Yanlong
Zhang, Xiuhua
Hu, Lufeng
author_facet Chen, Huiling
Yang, Bo
Liu, Dayou
Liu, Wenbin
Liu, Yanlong
Zhang, Xiuhua
Hu, Lufeng
author_sort Chen, Huiling
collection PubMed
description The number of the overweight people continues to rise across the world. Studies have shown that being overweight can increase health risks, such as high blood pressure, diabetes mellitus, coronary heart disease, and certain forms of cancer. Therefore, identifying the overweight status in people is critical to prevent and decrease health risks. This study explores a new technique that uses blood and biochemical measurements to recognize the overweight condition. A new machine learning technique, an extreme learning machine, was developed to accurately detect the overweight status from a pool of 225 overweight and 251 healthy subjects. The group included 179 males and 297 females. The detection method was rigorously evaluated against the real-life dataset for accuracy, sensitivity, specificity, and AUC (area under the receiver operating characteristic (ROC) curve) criterion. Additionally, the feature selection was investigated to identify correlating factors for the overweight status. The results demonstrate that there are significant differences in blood and biochemical indexes between healthy and overweight people (p-value < 0.01). According to the feature selection, the most important correlated indexes are creatinine, hemoglobin, hematokrit, uric Acid, red blood cells, high density lipoprotein, alanine transaminase, triglyceride, and γ-glutamyl transpeptidase. These are consistent with the results of Spearman test analysis. The proposed method holds promise as a new, accurate method for identifying the overweight status in subjects.
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spelling pubmed-46581462015-12-02 Using Blood Indexes to Predict Overweight Statuses: An Extreme Learning Machine-Based Approach Chen, Huiling Yang, Bo Liu, Dayou Liu, Wenbin Liu, Yanlong Zhang, Xiuhua Hu, Lufeng PLoS One Research Article The number of the overweight people continues to rise across the world. Studies have shown that being overweight can increase health risks, such as high blood pressure, diabetes mellitus, coronary heart disease, and certain forms of cancer. Therefore, identifying the overweight status in people is critical to prevent and decrease health risks. This study explores a new technique that uses blood and biochemical measurements to recognize the overweight condition. A new machine learning technique, an extreme learning machine, was developed to accurately detect the overweight status from a pool of 225 overweight and 251 healthy subjects. The group included 179 males and 297 females. The detection method was rigorously evaluated against the real-life dataset for accuracy, sensitivity, specificity, and AUC (area under the receiver operating characteristic (ROC) curve) criterion. Additionally, the feature selection was investigated to identify correlating factors for the overweight status. The results demonstrate that there are significant differences in blood and biochemical indexes between healthy and overweight people (p-value < 0.01). According to the feature selection, the most important correlated indexes are creatinine, hemoglobin, hematokrit, uric Acid, red blood cells, high density lipoprotein, alanine transaminase, triglyceride, and γ-glutamyl transpeptidase. These are consistent with the results of Spearman test analysis. The proposed method holds promise as a new, accurate method for identifying the overweight status in subjects. Public Library of Science 2015-11-23 /pmc/articles/PMC4658146/ /pubmed/26600199 http://dx.doi.org/10.1371/journal.pone.0143003 Text en © 2015 Chen et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Chen, Huiling
Yang, Bo
Liu, Dayou
Liu, Wenbin
Liu, Yanlong
Zhang, Xiuhua
Hu, Lufeng
Using Blood Indexes to Predict Overweight Statuses: An Extreme Learning Machine-Based Approach
title Using Blood Indexes to Predict Overweight Statuses: An Extreme Learning Machine-Based Approach
title_full Using Blood Indexes to Predict Overweight Statuses: An Extreme Learning Machine-Based Approach
title_fullStr Using Blood Indexes to Predict Overweight Statuses: An Extreme Learning Machine-Based Approach
title_full_unstemmed Using Blood Indexes to Predict Overweight Statuses: An Extreme Learning Machine-Based Approach
title_short Using Blood Indexes to Predict Overweight Statuses: An Extreme Learning Machine-Based Approach
title_sort using blood indexes to predict overweight statuses: an extreme learning machine-based approach
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658146/
https://www.ncbi.nlm.nih.gov/pubmed/26600199
http://dx.doi.org/10.1371/journal.pone.0143003
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