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Using Blood Indexes to Predict Overweight Statuses: An Extreme Learning Machine-Based Approach
The number of the overweight people continues to rise across the world. Studies have shown that being overweight can increase health risks, such as high blood pressure, diabetes mellitus, coronary heart disease, and certain forms of cancer. Therefore, identifying the overweight status in people is c...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658146/ https://www.ncbi.nlm.nih.gov/pubmed/26600199 http://dx.doi.org/10.1371/journal.pone.0143003 |
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author | Chen, Huiling Yang, Bo Liu, Dayou Liu, Wenbin Liu, Yanlong Zhang, Xiuhua Hu, Lufeng |
author_facet | Chen, Huiling Yang, Bo Liu, Dayou Liu, Wenbin Liu, Yanlong Zhang, Xiuhua Hu, Lufeng |
author_sort | Chen, Huiling |
collection | PubMed |
description | The number of the overweight people continues to rise across the world. Studies have shown that being overweight can increase health risks, such as high blood pressure, diabetes mellitus, coronary heart disease, and certain forms of cancer. Therefore, identifying the overweight status in people is critical to prevent and decrease health risks. This study explores a new technique that uses blood and biochemical measurements to recognize the overweight condition. A new machine learning technique, an extreme learning machine, was developed to accurately detect the overweight status from a pool of 225 overweight and 251 healthy subjects. The group included 179 males and 297 females. The detection method was rigorously evaluated against the real-life dataset for accuracy, sensitivity, specificity, and AUC (area under the receiver operating characteristic (ROC) curve) criterion. Additionally, the feature selection was investigated to identify correlating factors for the overweight status. The results demonstrate that there are significant differences in blood and biochemical indexes between healthy and overweight people (p-value < 0.01). According to the feature selection, the most important correlated indexes are creatinine, hemoglobin, hematokrit, uric Acid, red blood cells, high density lipoprotein, alanine transaminase, triglyceride, and γ-glutamyl transpeptidase. These are consistent with the results of Spearman test analysis. The proposed method holds promise as a new, accurate method for identifying the overweight status in subjects. |
format | Online Article Text |
id | pubmed-4658146 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-46581462015-12-02 Using Blood Indexes to Predict Overweight Statuses: An Extreme Learning Machine-Based Approach Chen, Huiling Yang, Bo Liu, Dayou Liu, Wenbin Liu, Yanlong Zhang, Xiuhua Hu, Lufeng PLoS One Research Article The number of the overweight people continues to rise across the world. Studies have shown that being overweight can increase health risks, such as high blood pressure, diabetes mellitus, coronary heart disease, and certain forms of cancer. Therefore, identifying the overweight status in people is critical to prevent and decrease health risks. This study explores a new technique that uses blood and biochemical measurements to recognize the overweight condition. A new machine learning technique, an extreme learning machine, was developed to accurately detect the overweight status from a pool of 225 overweight and 251 healthy subjects. The group included 179 males and 297 females. The detection method was rigorously evaluated against the real-life dataset for accuracy, sensitivity, specificity, and AUC (area under the receiver operating characteristic (ROC) curve) criterion. Additionally, the feature selection was investigated to identify correlating factors for the overweight status. The results demonstrate that there are significant differences in blood and biochemical indexes between healthy and overweight people (p-value < 0.01). According to the feature selection, the most important correlated indexes are creatinine, hemoglobin, hematokrit, uric Acid, red blood cells, high density lipoprotein, alanine transaminase, triglyceride, and γ-glutamyl transpeptidase. These are consistent with the results of Spearman test analysis. The proposed method holds promise as a new, accurate method for identifying the overweight status in subjects. Public Library of Science 2015-11-23 /pmc/articles/PMC4658146/ /pubmed/26600199 http://dx.doi.org/10.1371/journal.pone.0143003 Text en © 2015 Chen et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. |
spellingShingle | Research Article Chen, Huiling Yang, Bo Liu, Dayou Liu, Wenbin Liu, Yanlong Zhang, Xiuhua Hu, Lufeng Using Blood Indexes to Predict Overweight Statuses: An Extreme Learning Machine-Based Approach |
title | Using Blood Indexes to Predict Overweight Statuses: An Extreme Learning Machine-Based Approach |
title_full | Using Blood Indexes to Predict Overweight Statuses: An Extreme Learning Machine-Based Approach |
title_fullStr | Using Blood Indexes to Predict Overweight Statuses: An Extreme Learning Machine-Based Approach |
title_full_unstemmed | Using Blood Indexes to Predict Overweight Statuses: An Extreme Learning Machine-Based Approach |
title_short | Using Blood Indexes to Predict Overweight Statuses: An Extreme Learning Machine-Based Approach |
title_sort | using blood indexes to predict overweight statuses: an extreme learning machine-based approach |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658146/ https://www.ncbi.nlm.nih.gov/pubmed/26600199 http://dx.doi.org/10.1371/journal.pone.0143003 |
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