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The Impact of PNPLA3 rs738409 SNP on Liver Fibrosis Progression, Portal Hypertension and Hepatic Steatosis in HIV/HCV Coinfection

BACKGROUND: Faster fibrosis progression and hepatic steatosis are hallmarks of HIV/HCV coinfection. A single nucleotide polymorphism (SNP) of the PNPLA3-gene is associated with development of non-alcoholic steatohepatitis and a worse outcome in alcoholic liver disease. However, the role of PNPLA3 rs...

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Detalles Bibliográficos
Autores principales:	Scheiner, Bernhard, Mandorfer, Mattias, Schwabl, Philipp, Payer, Berit Anna, Bucsics, Theresa, Bota, Simona, Aichelburg, Maximilian C., Grabmeier-Pfistershammer, Katharina, Stättermayer, Albert, Ferenci, Peter, Trauner, Michael, Peck-Radosavljevic, Markus, Reiberger, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658167/ https://www.ncbi.nlm.nih.gov/pubmed/26599080 http://dx.doi.org/10.1371/journal.pone.0143429

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