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Single-molecule fluorimetry and gating currents inspire an improved optical voltage indicator
Voltage-sensing domains (VSDs) underlie the movement of voltage-gated ion channels, as well as the voltage-sensitive fluorescent responses observed from a common class of genetically encoded voltage indicators (GEVIs). Despite the widespread use and potential utility of these GEVIs, the biophysical...
Autores principales: | Treger, Jeremy S, Priest, Michael F, Bezanilla, Francisco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658195/ https://www.ncbi.nlm.nih.gov/pubmed/26599732 http://dx.doi.org/10.7554/eLife.10482 |
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