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Identification and activity of inhibitors of the essential nematode-specific metalloprotease DPY-31
Infection by parasitic nematodes is widespread in the developing world causing extensive morbidity and mortality. Furthermore, infection of animals is a global problem, with a substantial impact on food production. Here we identify small molecule inhibitors of a nematode-specific metalloprotease, DP...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Science Ltd
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658336/ https://www.ncbi.nlm.nih.gov/pubmed/26546217 http://dx.doi.org/10.1016/j.bmcl.2015.10.077 |