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Identification of a Ligand Binding Pocket in LdtR from Liberibacter asiaticus
LdtR is a transcriptional activator involved in the regulation of a putative L,D transpeptidase in Liberibacter asiaticus, an unculturable pathogen and one of the causative agents of Huanglongbing disease. Using small molecule screens we identified benzbromarone as an inhibitor of LdtR activity, whi...
Autores principales: | Pagliai, Fernando A., Gonzalez, Claudio F., Lorca, Graciela L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658428/ https://www.ncbi.nlm.nih.gov/pubmed/26635775 http://dx.doi.org/10.3389/fmicb.2015.01314 |
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