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A Diverse Repertoire of CD4 T Cells Targets the Immediate-Early 1 Protein of Human Cytomegalovirus

T-cell responses to the immediate-early 1 (IE-1) protein of human cytomegalovirus (HCMV) are associated with protection from viral disease. Thus, IE-1 is a promising target for immunotherapy. CD8 T-cell responses to IE-1 are generally strong. In contrast, CD4 T-cell responses to IE-1 were described...

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Detalles Bibliográficos
Autores principales: Ameres, Stefanie, Liang, Xiaoling, Wiesner, Martina, Mautner, Josef, Moosmann, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658442/
https://www.ncbi.nlm.nih.gov/pubmed/26635812
http://dx.doi.org/10.3389/fimmu.2015.00598