Improvement of the Targeting of Radiolabeled and Functionalized Liposomes with a Two-Step System Using a Bispecific Monoclonal Antibody (Anti-CEA × Anti-DTPA–In)

This study proposes liposomes as a new tool for pretargeted radioimmunotherapy (RIT) in solid tumors. Tumor pretargeting is obtained by using a bispecific monoclonal antibody [BsmAb, anti-CEA × anti-DTPA-indium complex (DTPA–In)] and pegylated radioactive liposomes containing a lipid-hapten conjugat...

Descripción completa

Detalles Bibliográficos
Autores principales: Rauscher, Aurore, Frindel, Mathieu, Rajerison, Holisoa, Gouard, Sébastien, Maurel, Catherine, Barbet, Jacques, Faivre-Chauvet, Alain, Mougin-Degraef, Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658472/
https://www.ncbi.nlm.nih.gov/pubmed/26636087
http://dx.doi.org/10.3389/fmed.2015.00083

Ejemplares similares

Ejemplares similares