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Phenotypic and genomic comparisons of highly vancomycin-resistant Staphylococcus aureus strains developed from multiple clinical MRSA strains by in vitro mutagenesis
The development of vancomycin (VCM) resistance in Staphylococcus aureus threatens global health. Studies of the VCM-resistance mechanism and alternative therapeutic strategies are urgently needed. We mutagenized S. aureus laboratory strains and methicillin-resistant S. aureus (MRSA) with ethyl metha...
Autores principales: | Ishii, Kenichi, Tabuchi, Fumiaki, Matsuo, Miki, Tatsuno, Keita, Sato, Tomoaki, Okazaki, Mitsuhiro, Hamamoto, Hiroshi, Matsumoto, Yasuhiko, Kaito, Chikara, Aoyagi, Tetsuji, Hiramatsu, Keiichi, Kaku, Mitsuo, Moriya, Kyoji, Sekimizu, Kazuhisa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658547/ https://www.ncbi.nlm.nih.gov/pubmed/26603341 http://dx.doi.org/10.1038/srep17092 |
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