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TVB-EduPack—An Interactive Learning and Scripting Platform for The Virtual Brain

The Virtual Brain (TVB; thevirtualbrain.org) is a neuroinformatics platform for full brain network simulation based on individual anatomical connectivity data. The framework addresses clinical and neuroscientific questions by simulating multi-scale neural dynamics that range from local population ac...

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Autores principales: Matzke, Henrik, Schirner, Michael, Vollbrecht, Daniel, Rothmeier, Simon, Llarena, Adalberto, Rojas, Raúl, Triebkorn, Paul, Domide, Lia, Mersmann, Jochen, Solodkin, Ana, Jirsa, Viktor K., McIntosh, Anthony Randal, Ritter, Petra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658631/
https://www.ncbi.nlm.nih.gov/pubmed/26635597
http://dx.doi.org/10.3389/fninf.2015.00027
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author Matzke, Henrik
Schirner, Michael
Vollbrecht, Daniel
Rothmeier, Simon
Llarena, Adalberto
Rojas, Raúl
Triebkorn, Paul
Domide, Lia
Mersmann, Jochen
Solodkin, Ana
Jirsa, Viktor K.
McIntosh, Anthony Randal
Ritter, Petra
author_facet Matzke, Henrik
Schirner, Michael
Vollbrecht, Daniel
Rothmeier, Simon
Llarena, Adalberto
Rojas, Raúl
Triebkorn, Paul
Domide, Lia
Mersmann, Jochen
Solodkin, Ana
Jirsa, Viktor K.
McIntosh, Anthony Randal
Ritter, Petra
author_sort Matzke, Henrik
collection PubMed
description The Virtual Brain (TVB; thevirtualbrain.org) is a neuroinformatics platform for full brain network simulation based on individual anatomical connectivity data. The framework addresses clinical and neuroscientific questions by simulating multi-scale neural dynamics that range from local population activity to large-scale brain function and related macroscopic signals like electroencephalography and functional magnetic resonance imaging. TVB is equipped with a graphical and a command-line interface to create models that capture the characteristic biological variability to predict the brain activity of individual subjects. To enable researchers from various backgrounds a quick start into TVB and brain network modeling in general, we developed an educational module: TVB-EduPack. EduPack offers two educational functionalities that seamlessly integrate into TVB's graphical user interface (GUI): (i) interactive tutorials introduce GUI elements, guide through the basic mechanics of software usage and develop complex use-case scenarios; animations, videos and textual descriptions transport essential principles of computational neuroscience and brain modeling; (ii) an automatic script generator records model parameters and produces input files for TVB's Python programming interface; thereby, simulation configurations can be exported as scripts that allow flexible customization of the modeling process and self-defined batch- and post-processing applications while benefitting from the full power of the Python language and its toolboxes. This article covers the implementation of TVB-EduPack and its integration into TVB architecture. Like TVB, EduPack is an open source community project that lives from the participation and contribution of its users. TVB-EduPack can be obtained as part of TVB from thevirtualbrain.org.
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spelling pubmed-46586312015-12-03 TVB-EduPack—An Interactive Learning and Scripting Platform for The Virtual Brain Matzke, Henrik Schirner, Michael Vollbrecht, Daniel Rothmeier, Simon Llarena, Adalberto Rojas, Raúl Triebkorn, Paul Domide, Lia Mersmann, Jochen Solodkin, Ana Jirsa, Viktor K. McIntosh, Anthony Randal Ritter, Petra Front Neuroinform Neuroscience The Virtual Brain (TVB; thevirtualbrain.org) is a neuroinformatics platform for full brain network simulation based on individual anatomical connectivity data. The framework addresses clinical and neuroscientific questions by simulating multi-scale neural dynamics that range from local population activity to large-scale brain function and related macroscopic signals like electroencephalography and functional magnetic resonance imaging. TVB is equipped with a graphical and a command-line interface to create models that capture the characteristic biological variability to predict the brain activity of individual subjects. To enable researchers from various backgrounds a quick start into TVB and brain network modeling in general, we developed an educational module: TVB-EduPack. EduPack offers two educational functionalities that seamlessly integrate into TVB's graphical user interface (GUI): (i) interactive tutorials introduce GUI elements, guide through the basic mechanics of software usage and develop complex use-case scenarios; animations, videos and textual descriptions transport essential principles of computational neuroscience and brain modeling; (ii) an automatic script generator records model parameters and produces input files for TVB's Python programming interface; thereby, simulation configurations can be exported as scripts that allow flexible customization of the modeling process and self-defined batch- and post-processing applications while benefitting from the full power of the Python language and its toolboxes. This article covers the implementation of TVB-EduPack and its integration into TVB architecture. Like TVB, EduPack is an open source community project that lives from the participation and contribution of its users. TVB-EduPack can be obtained as part of TVB from thevirtualbrain.org. Frontiers Media S.A. 2015-11-25 /pmc/articles/PMC4658631/ /pubmed/26635597 http://dx.doi.org/10.3389/fninf.2015.00027 Text en Copyright © 2015 Matzke, Schirner, Vollbrecht, Rothmeier, Llarena, Rojas, Triebkorn, Domide, Mersmann, Solodkin, Jirsa, McIntosh and Ritter. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Matzke, Henrik
Schirner, Michael
Vollbrecht, Daniel
Rothmeier, Simon
Llarena, Adalberto
Rojas, Raúl
Triebkorn, Paul
Domide, Lia
Mersmann, Jochen
Solodkin, Ana
Jirsa, Viktor K.
McIntosh, Anthony Randal
Ritter, Petra
TVB-EduPack—An Interactive Learning and Scripting Platform for The Virtual Brain
title TVB-EduPack—An Interactive Learning and Scripting Platform for The Virtual Brain
title_full TVB-EduPack—An Interactive Learning and Scripting Platform for The Virtual Brain
title_fullStr TVB-EduPack—An Interactive Learning and Scripting Platform for The Virtual Brain
title_full_unstemmed TVB-EduPack—An Interactive Learning and Scripting Platform for The Virtual Brain
title_short TVB-EduPack—An Interactive Learning and Scripting Platform for The Virtual Brain
title_sort tvb-edupack—an interactive learning and scripting platform for the virtual brain
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658631/
https://www.ncbi.nlm.nih.gov/pubmed/26635597
http://dx.doi.org/10.3389/fninf.2015.00027
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