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A new application of click chemistry in situ: development of fluorescent probe for specific G-quadruplex topology
Target-guided synthesis is an approach to drug discovery that allows the target to self-assemble its own binding agents. So far, target-guided synthesis and especially in situ click chemistry have attracted extensive attention and have led to the identification of highly potent inhibitors for protei...
Autores principales: | Hu, Ming-Hao, Chen, Xiao, Chen, Shuo-Bin, Ou, Tian-Miao, Yao, Meicun, Gu, Lian-Quan, Huang, Zhi-Shu, Tan, Jia-Heng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658637/ https://www.ncbi.nlm.nih.gov/pubmed/26603780 http://dx.doi.org/10.1038/srep17202 |
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