Individual protomers of a G protein-coupled receptor dimer integrate distinct functional modules

Recent advances in proteomic technology reveal G-protein-coupled receptors (GPCRs) are organized as large, macromolecular protein complexes in cell membranes, adding a new layer of intricacy to GPCR signaling. We previously reported the α(1D)-adrenergic receptor (ADRA1D)—a key regulator of cardiovas...

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Detalles Bibliográficos
Autores principales: Camp, Nathan D, Lee, Kyung-Soon, Wacker-Mhyre, Jennifer L, Kountz, Timothy S, Park, Ji-Min, Harris, Dorathy-Ann, Estrada, Marianne, Stewart, Aaron, Wolf-Yadlin, Alejandro, Hague, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658663/
https://www.ncbi.nlm.nih.gov/pubmed/26617989
http://dx.doi.org/10.1038/celldisc.2015.11

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658663/
https://www.ncbi.nlm.nih.gov/pubmed/26617989
http://dx.doi.org/10.1038/celldisc.2015.11

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