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Individual protomers of a G protein-coupled receptor dimer integrate distinct functional modules
Recent advances in proteomic technology reveal G-protein-coupled receptors (GPCRs) are organized as large, macromolecular protein complexes in cell membranes, adding a new layer of intricacy to GPCR signaling. We previously reported the α(1D)-adrenergic receptor (ADRA1D)—a key regulator of cardiovas...
Autores principales: | Camp, Nathan D, Lee, Kyung-Soon, Wacker-Mhyre, Jennifer L, Kountz, Timothy S, Park, Ji-Min, Harris, Dorathy-Ann, Estrada, Marianne, Stewart, Aaron, Wolf-Yadlin, Alejandro, Hague, Chris |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658663/ https://www.ncbi.nlm.nih.gov/pubmed/26617989 http://dx.doi.org/10.1038/celldisc.2015.11 |
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