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Granulocyte colony-stimulating factor exacerbates hematopoietic stem cell injury after irradiation

BACKGROUND: Exposure to a moderate to high dose of ionizing radiation (IR) not only causes acute radiation syndrome but also induces long-term (LT) bone marrow (BM) injury. The latter effect of IR is primarily attributed to the induction of hematopoietic stem cell (HSC) senescence. Granulocyte colon...

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Detalles Bibliográficos
Autores principales:	Li, Chengcheng, Lu, Lu, Zhang, Junling, Huang, Song, Xing, Yonghua, Zhao, Mingfeng, Zhou, Daohong, Li, Deguan, Meng, Aimin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4659162/ https://www.ncbi.nlm.nih.gov/pubmed/26609358 http://dx.doi.org/10.1186/s13578-015-0057-3

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