Ethnicity-specific epigenetic variation in naïve CD4+ T cells and the susceptibility to autoimmunity

BACKGROUND: Genetic and epigenetic variability contributes to the susceptibility and pathogenesis of autoimmune diseases. T cells play an important role in several autoimmune conditions, including lupus, which is more common and more severe in people of African descent. To investigate inherent epige...

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Detalles Bibliográficos
Autores principales: Coit, Patrick, Ognenovski, Mikhail, Gensterblum, Elizabeth, Maksimowicz-McKinnon, Kathleen, Wren, Jonathan D., Sawalha, Amr H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4659164/
https://www.ncbi.nlm.nih.gov/pubmed/26609326
http://dx.doi.org/10.1186/s13072-015-0037-1

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