Evaluation of chromosome aberrations induced by digoxin in Chinese hamster ovary cells

Digoxin is a cardiac glycoside that has been reported to inhibit growth of multiple tumor cell types in vitro. The present study was assessing the cytogenetic effects of this drug on Chinese Hamster Ovary (CHO) cells. All experiments were performed in triplicate. The IC(50) was 22.5 ± 0.8 µg/ml. To...

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Detalles Bibliográficos
Autores principales: Sedigh-Ardekani, Mozhgan, Saadat, Iraj, Saadat, Mostafa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Leibniz Research Centre for Working Environment and Human Factors 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4659336/
https://www.ncbi.nlm.nih.gov/pubmed/26622212

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