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c-Met as a Target for Personalized Therapy
MET and its ligand HGF are involved in many biological processes, both physiological and pathological, making this signaling pathway an attractive therapeutic target in oncology. Downstream signaling effects are transmitted via mitogen-activated protein kinase (MAPK), PI3K (phosphoinositide 3-kinase...
Autores principales: | Garajová, Ingrid, Giovannetti, Elisa, Biasco, Guido, Peters, Godefridus J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Libertas Academica
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4659440/ https://www.ncbi.nlm.nih.gov/pubmed/26628860 http://dx.doi.org/10.4137/TOG.S30534 |
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