Use of a High-Density Protein Microarray to Identify Autoantibodies in Subjects with Type 2 Diabetes Mellitus and an HLA Background Associated with Reduced Insulin Secretion

New biomarkers for type 2 diabetes mellitus (T2DM) may aid diagnosis, drug development or clinical treatment. Evidence is increasing for the adaptive immune system’s role in T2DM and suggests the presence of unidentified autoantibodies. While high-density protein microarrays have emerged as a useful...

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Detalles Bibliográficos
Autores principales: Chang, Douglas C., Piaggi, Paolo, Hanson, Robert L., Knowler, William C., Bucci, John, Thio, Guene, Hohenadel, Maximilian G., Bogardus, Clifton, Krakoff, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4659622/
https://www.ncbi.nlm.nih.gov/pubmed/26606528
http://dx.doi.org/10.1371/journal.pone.0143551

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4659622/
https://www.ncbi.nlm.nih.gov/pubmed/26606528
http://dx.doi.org/10.1371/journal.pone.0143551

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