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Use of a High-Density Protein Microarray to Identify Autoantibodies in Subjects with Type 2 Diabetes Mellitus and an HLA Background Associated with Reduced Insulin Secretion
New biomarkers for type 2 diabetes mellitus (T2DM) may aid diagnosis, drug development or clinical treatment. Evidence is increasing for the adaptive immune system’s role in T2DM and suggests the presence of unidentified autoantibodies. While high-density protein microarrays have emerged as a useful...
Autores principales: | Chang, Douglas C., Piaggi, Paolo, Hanson, Robert L., Knowler, William C., Bucci, John, Thio, Guene, Hohenadel, Maximilian G., Bogardus, Clifton, Krakoff, Jonathan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4659622/ https://www.ncbi.nlm.nih.gov/pubmed/26606528 http://dx.doi.org/10.1371/journal.pone.0143551 |
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