Cargando…
A Versatile Strategy for Production of Membrane Proteins with Diverse Topologies: Application to Investigation of Bacterial Homologues of Human Divalent Metal Ion and Nucleoside Transporters
Membrane proteins play key roles in many biological processes, from acquisition of nutrients to neurotransmission, and are targets for more than 50% of current therapeutic drugs. However, their investigation is hampered by difficulties in their production and purification on a scale suitable for str...
Autores principales: | Ma, Cheng, Hao, Zhenyu, Huysmans, Gerard, Lesiuk, Amelia, Bullough, Per, Wang, Yingying, Bartlam, Mark, Phillips, Simon E., Young, James D., Goldman, Adrian, Baldwin, Stephen A., Postis, Vincent L. G. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4659628/ https://www.ncbi.nlm.nih.gov/pubmed/26606682 http://dx.doi.org/10.1371/journal.pone.0143010 |
Ejemplares similares
-
A Novel and Fast Purification Method for Nucleoside Transporters
por: Hao, Zhenyu, et al.
Publicado: (2016) -
Transport mechanism of a glutamate transporter homologue Glt(Ph)
por: Ji, Yurui, et al.
Publicado: (2016) -
Use of molecular modelling to probe the mechanism of the nucleoside transporter NupG
por: Vaziri, Hamidreza, et al.
Publicado: (2013) -
Torpedo californica acetylcholinesterase is stabilized by binding of a divalent metal ion to a novel and versatile 4D motif
por: Silman, Israel, et al.
Publicado: (2021) -
The high‐energy transition state of the glutamate transporter homologue GltPh
por: Huysmans, Gerard H M, et al.
Publicado: (2020)