Cargando…
Optimization of Methods for the Genetic Modification of Human T Cells
CD4+ T cells are critical in the fight against parasitic, bacterial, and viral infections, but are also involved in many autoimmune and pathological disorders. Studies of protein function in human T cells are confined to techniques such as RNAi due to ethical reasons and relative simplicity of these...
Autores principales: | Bilal, Mahmood Y., Vacaflores, Aldo, Houtman, Jon C.D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4659746/ https://www.ncbi.nlm.nih.gov/pubmed/26027856 http://dx.doi.org/10.1038/icb.2015.59 |
Ejemplares similares
-
Exposure of Human CD4 T Cells to IL-12 Results in Enhanced TCR-Induced Cytokine Production, Altered TCR Signaling, and Increased Oxidative Metabolism
por: Vacaflores, Aldo, et al.
Publicado: (2016) -
GRB2 Nucleates T Cell Receptor-Mediated LAT Clusters That Control PLC-γ1 Activation and Cytokine Production
por: Bilal, Mahmood Yousif, et al.
Publicado: (2015) -
Human Serum Albumin (HSA) Suppresses the Effects of Glycerol Monolaurate (GML) on Human T Cell Activation and Function
por: Zhang, Michael S., et al.
Publicado: (2016) -
Genetic Cell-Surface Modification for Optimized Foam Fractionation
por: Blesken, Christian C., et al.
Publicado: (2020) -
Glycerol Monolaurate (GML) inhibits human T cell signaling and function by disrupting lipid dynamics
por: Zhang, Michael S., et al.
Publicado: (2016)