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Identification of genes escaping X inactivation by allelic expression analysis in a novel hybrid mouse model
X chromosome inactivation (XCI) is a female-specific mechanism that serves to balance gene dosage between the sexes whereby one X chromosome in females is inactivated during early development. Despite this silencing, a small portion of genes escape inactivation and remain expressed from the inactive...
Autores principales: | Berletch, Joel B., Ma, Wenxiu, Yang, Fan, Shendure, Jay, Noble, William S., Disteche, Christine M., Deng, Xinxian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4659812/ https://www.ncbi.nlm.nih.gov/pubmed/26693509 http://dx.doi.org/10.1016/j.dib.2015.10.033 |
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