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X-ray structure and activities of an essential Mononegavirales L-protein domain

The L protein of mononegaviruses harbours all catalytic activities for genome replication and transcription. It contains six conserved domains (CR-I to -VI; Fig. 1a). CR-III has been linked to polymerase and polyadenylation activity, CR-V to mRNA capping and CR-VI to cap methylation. However, how th...

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Detalles Bibliográficos
Autores principales:	Paesen, Guido C., Collet, Axelle, Sallamand, Corinne, Debart, Françoise, Vasseur, Jean-Jacques, Canard, Bruno, Decroly, Etienne, Grimes, Jonathan M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4659945/ https://www.ncbi.nlm.nih.gov/pubmed/26549102 http://dx.doi.org/10.1038/ncomms9749

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