Docosahexaenoic Acid Modulates a HER2-Associated Lipogenic Phenotype, Induces Apoptosis, and Increases Trastuzumab Action in HER2-Overexpressing Breast Carcinoma Cells

In breast cancer, lipid metabolic alterations have been recognized as potential oncogenic stimuli that may promote malignancy. To investigate whether the oncogenic nature of lipogenesis closely depends on the overexpression of HER2 protooncogene, the normal breast cell line, HB4a, was transfected wi...

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Detalles Bibliográficos
Autores principales: Ravacci, Graziela Rosa, Brentani, Maria Mitzi, Tortelli, Tharcisio Citrângulo, Torrinhas, Raquel Suzana M. M., Santos, Jéssica Reis, Logullo, Angela Flávia, Waitzberg, Dan Linetzky
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4659962/
https://www.ncbi.nlm.nih.gov/pubmed/26640797
http://dx.doi.org/10.1155/2015/838652

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