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A Case of Idiopathic Hypereosinophilic Syndrome Causing Mitral Valve Papillary Muscle Rupture

Idiopathic Hypereosinophilic Syndrome (IHES) is a rare disease that can be difficult to diagnose as the differential is broad. This disease can cause significant morbidity and mortality if left untreated. Our patient is a 17-year-old adolescent female who presented with nonspecific symptoms of abdom...

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Autores principales: Tamse, Tiffany, Rampersad, Avind, Jordan-Villegas, Alejandro, Ireland, Jill
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660015/
https://www.ncbi.nlm.nih.gov/pubmed/26640733
http://dx.doi.org/10.1155/2015/538762
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author Tamse, Tiffany
Rampersad, Avind
Jordan-Villegas, Alejandro
Ireland, Jill
author_facet Tamse, Tiffany
Rampersad, Avind
Jordan-Villegas, Alejandro
Ireland, Jill
author_sort Tamse, Tiffany
collection PubMed
description Idiopathic Hypereosinophilic Syndrome (IHES) is a rare disease that can be difficult to diagnose as the differential is broad. This disease can cause significant morbidity and mortality if left untreated. Our patient is a 17-year-old adolescent female who presented with nonspecific symptoms of abdominal pain and malaise. She was incidentally found to have hypereosinophilia of 16,000 on complete blood count and nonspecific colitis and pulmonary edema on computed tomography. She went into cardiogenic shock due to papillary rupture of her mitral valve requiring extreme life support measures including intubation and extracorporal membrane oxygenation (ECMO) as well as mitral valve replacement. Pathology of the valve showed eosinophilic infiltration as the underlying etiology. The patient was diagnosed with IHES after the exclusion of infectious, rheumatologic, and oncologic causes. She was treated with steroids with improvement of her symptoms and scheduled for close follow-up. In general patients with IHES that have cardiac involvement have poorer prognoses.
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spelling pubmed-46600152015-12-06 A Case of Idiopathic Hypereosinophilic Syndrome Causing Mitral Valve Papillary Muscle Rupture Tamse, Tiffany Rampersad, Avind Jordan-Villegas, Alejandro Ireland, Jill Case Rep Pediatr Case Report Idiopathic Hypereosinophilic Syndrome (IHES) is a rare disease that can be difficult to diagnose as the differential is broad. This disease can cause significant morbidity and mortality if left untreated. Our patient is a 17-year-old adolescent female who presented with nonspecific symptoms of abdominal pain and malaise. She was incidentally found to have hypereosinophilia of 16,000 on complete blood count and nonspecific colitis and pulmonary edema on computed tomography. She went into cardiogenic shock due to papillary rupture of her mitral valve requiring extreme life support measures including intubation and extracorporal membrane oxygenation (ECMO) as well as mitral valve replacement. Pathology of the valve showed eosinophilic infiltration as the underlying etiology. The patient was diagnosed with IHES after the exclusion of infectious, rheumatologic, and oncologic causes. She was treated with steroids with improvement of her symptoms and scheduled for close follow-up. In general patients with IHES that have cardiac involvement have poorer prognoses. Hindawi Publishing Corporation 2015 2015-11-12 /pmc/articles/PMC4660015/ /pubmed/26640733 http://dx.doi.org/10.1155/2015/538762 Text en Copyright © 2015 Tiffany Tamse et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Tamse, Tiffany
Rampersad, Avind
Jordan-Villegas, Alejandro
Ireland, Jill
A Case of Idiopathic Hypereosinophilic Syndrome Causing Mitral Valve Papillary Muscle Rupture
title A Case of Idiopathic Hypereosinophilic Syndrome Causing Mitral Valve Papillary Muscle Rupture
title_full A Case of Idiopathic Hypereosinophilic Syndrome Causing Mitral Valve Papillary Muscle Rupture
title_fullStr A Case of Idiopathic Hypereosinophilic Syndrome Causing Mitral Valve Papillary Muscle Rupture
title_full_unstemmed A Case of Idiopathic Hypereosinophilic Syndrome Causing Mitral Valve Papillary Muscle Rupture
title_short A Case of Idiopathic Hypereosinophilic Syndrome Causing Mitral Valve Papillary Muscle Rupture
title_sort case of idiopathic hypereosinophilic syndrome causing mitral valve papillary muscle rupture
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660015/
https://www.ncbi.nlm.nih.gov/pubmed/26640733
http://dx.doi.org/10.1155/2015/538762
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