Cargando…
Simulation work in adaptive dose-finding designs to identify dose-intervals that achieve targets in multiple endpoints
Autores principales: | Howlett, James, Bond, Simon, Mander, Adrian, Todd, John, Wicker, Linda, Waldron-Lynch, Frank |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660131/ http://dx.doi.org/10.1186/1745-6215-16-S2-P217 |
Ejemplares similares
-
Adaptive dose-finding designs to identify multiple doses that achieve multiple response targets
por: Bond, Simon, et al.
Publicado: (2013) -
Rationale and study design of the Adaptive study of IL-2 dose on regulatory T cells in type 1 diabetes (DILT1D): a non-randomised, open label, adaptive dose finding trial
por: Waldron-Lynch, Frank, et al.
Publicado: (2014) -
Protocol of the adaptive study of IL-2 dose frequency on regulatory T cells in type 1 diabetes (DILfrequency): a mechanistic, non-randomised, repeat dose, open-label, response-adaptive study
por: Truman, Lucy A, et al.
Publicado: (2015) -
Regulatory T Cell Responses in Participants with Type 1 Diabetes after a Single Dose of Interleukin-2: A Non-Randomised, Open Label, Adaptive Dose-Finding Trial
por: Todd, John A., et al.
Publicado: (2016) -
Seamless phase IIa/IIb adaptive design with the same primary endpoint for proof of concept and dose finding
por: Yuan, Jiacheng, et al.
Publicado: (2018)