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Fluid shear triggers microvilli formation via mechanosensitive activation of TRPV6

Microvilli are cellular membrane protrusions present on differentiated epithelial cells, which can sense and interact with the surrounding fluid environment. Biochemical and genetic approaches have identified a set of factors involved in microvilli formation; however, the underlying extrinsic regula...

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Detalles Bibliográficos
Autores principales: Miura, Shigenori, Sato, Koji, Kato-Negishi, Midori, Teshima, Tetsuhiko, Takeuchi, Shoji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660203/
https://www.ncbi.nlm.nih.gov/pubmed/26563429
http://dx.doi.org/10.1038/ncomms9871