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MicroRNA–mRNA interactions underlying colorectal cancer molecular subtypes

Colorectal cancer (CRC) transcriptional subtypes have been recently identified by gene expression profiling. Here we describe an analytical pipeline, microRNA master regulator analysis (MMRA), developed to search for microRNAs potentially driving CRC subtypes. Starting from a microRNA–mRNA tumour ex...

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Detalles Bibliográficos
Autores principales: Cantini, Laura, Isella, Claudio, Petti, Consalvo, Picco, Gabriele, Chiola, Simone, Ficarra, Elisa, Caselle, Michele, Medico, Enzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660217/
https://www.ncbi.nlm.nih.gov/pubmed/27305450
http://dx.doi.org/10.1038/ncomms9878