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Protein-protein interaction networks identify targets which rescue the MPP(+) cellular model of Parkinson’s disease

Neurodegenerative diseases are complex multifactorial disorders characterised by the interplay of many dysregulated physiological processes. As an exemplar, Parkinson’s disease (PD) involves multiple perturbed cellular functions, including mitochondrial dysfunction and autophagic dysregulation in pr...

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Detalles Bibliográficos
Autores principales: Keane, Harriet, Ryan, Brent J., Jackson, Brendan, Whitmore, Alan, Wade-Martins, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660280/
https://www.ncbi.nlm.nih.gov/pubmed/26608097
http://dx.doi.org/10.1038/srep17004