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Fitting Proportional Odds Model to Case-Control data with Incorporating Hardy-Weinberg Equilibrium
Genetic association studies have been proved to be an efficient tool to reveal the aetiology of many human complex diseases and traits. When the phenotype is binary, the logistic regression model is commonly employed to evaluate the association strength of the genetic variants predispose to human di...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660314/ https://www.ncbi.nlm.nih.gov/pubmed/26607176 http://dx.doi.org/10.1038/srep17286 |