Cargando…

Addressing the barriers to implementing model based designs in dose escalation studies

Detalles Bibliográficos
Autores principales:	Cornelius, Victoria, Bond, Simon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Poster Presentation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660329/ http://dx.doi.org/10.1186/1745-6215-16-S2-P235

Ejemplares similares

Some small sample properties of the EWOC design in dose escalation trials
por: Kinnersley, Nelson
Publicado: (2015)

PK/PD modeling supports the dose-escalation decision in VIKING
por: Lovern, M, et al.
Publicado: (2010)

Simulation work in adaptive dose-finding designs to identify dose-intervals that achieve targets in multiple endpoints
por: Howlett, James, et al.
Publicado: (2015)

The transfer of genetically engineered lymphocytes in melanoma patients: a Phase I dose escalation study
por: Regan, Courtney, et al.
Publicado: (2015)

A novel Bayesian method for dual-agent Phase I dose-escalation studies using penalized D-optimality
por: Wheeler, Graham
Publicado: (2013)

Phase I, dose-escalation, clinical trial of MVA-Brachyury-TRICOM vaccine demonstrating safety and brachyury-specific T cell responses
por: Heery, Christopher R, et al.
Publicado: (2015)

Phase 1 dose escalation of ONT-10, a therapeutic MUC1 vaccine, in patients with advanced cancer
por: Nemunaitis, John, et al.
Publicado: (2013)

Implementation of treatment escalation plans in a community psychiatric hospital
por: Chua, Anne Yan Ting, et al.
Publicado: (2021)

A dose-escalation clinical trial to evaluate the safety and immunogenicity of a replication-defective HIV-1 vaccine-HIVAX
por: Tung, F, et al.
Publicado: (2012)

Challenges of implementing multiple imputation to address missing data in economic evaluations
por: Fernandez, Aida Moure, et al.
Publicado: (2015)

Are there any Pinus pinaster trees resistant to Bursaphelenchus xylophilus? Studies implemented in Portugal to address this question
por: Costa, Rita, et al.
Publicado: (2011)

De-escalation of empiric antibiotic therapy in sepsis - an indian observational study
por: Jakkinaboina, S, et al.
Publicado: (2015)

De-escalation practice pattern in an Indian intensive care unit
por: Bhakta, A, et al.
Publicado: (2010)

Preliminary results of a triple peptide escalating dose vaccination phase I/II clinical trial as consolidation treatment in women affected by ovarian cancer
por: Napoletano, Chiara, et al.
Publicado: (2013)

Antibiotic costs in bacteremic and nonbacteremic patients treated with the de-escalation approach
por: Evodia, E, et al.
Publicado: (2008)

Forecasting escalation of cardio-respiratory instability using noninvasive vital sign monitoring data
por: Guillame-Bert, M, et al.
Publicado: (2015)

De-escalation of antimicrobial therapy in Gram-negative sepsis: easier said than done?
por: Phee, L, et al.
Publicado: (2011)

De-escalation therapy: 1-year experience in a general intensive care unit
por: Gyurov, E, et al.
Publicado: (2005)

Studying the effects of thalamic interneurons in a thalamocortical neural mass model
por: Bond, Thomas, et al.
Publicado: (2014)

Experiences in the design and implementation of phase II trials in CLL
por: Cohen, Dena R, et al.
Publicado: (2011)

Model-based optimization of peep, a strategy and its implementation
por: Rees, SE, et al.
Publicado: (2015)

Adaptive dose-finding designs to identify multiple doses that achieve multiple response targets
por: Bond, Simon, et al.
Publicado: (2013)

Model selection and sample size adaptation: HYPAZ trial
por: Bond, Simon, et al.
Publicado: (2011)

Design and implementation of needs-specific critical care response teams
por: Hodder, R, et al.
Publicado: (2007)

Adaptive designs for phase II cross-over dose-finding trials using Bayesian model averaging
por: Simpson, Sarah, et al.
Publicado: (2015)

A Phase I, open-label, dose escalation study of MGA271 in combination with ipilimumab in patients with B7-H3-expressing melanoma, squamous cell cancer of the head and neck or non-small cell lung cancer
por: Urba, Walter, et al.
Publicado: (2015)

A toxicity-dependent feasibility bound for the escalation with overdose control approach in phase I cancer trials
por: Wheeler, Graham, et al.
Publicado: (2015)

Software tools for implementing simulation studies in adaptive seamless designs: introducing R package ASD
por: Parsons, Nick, et al.
Publicado: (2011)

Barriers to the implementation of checklists in the ICU: a survey on the perceptions of 314 Brazilian critical care nurses and physicians
por: Salluh, J, et al.
Publicado: (2015)

Effects of different doses and serotypes of LPS on blood-brain barrier permeability in Sprague-Dawley rats
por: Senturk, E, et al.
Publicado: (2013)

Model-based design of the first steps of a seed train for cell culture processes
por: Kern, Simon, et al.
Publicado: (2013)

PSII-B-23 Implementation of a design thinking approach to problem-based learning in an animal science capstone
por: Paudyal, Sushil, et al.
Publicado: (2021)

A Phase I, open-label, dose escalation study of MGA271 in combination with pembrolizumab in patients with B7-H3-expressing melanoma, squamous cell cancer of the head and neck, or squamous cell non-small cell lung cancer
por: Baughman, Jan, et al.
Publicado: (2015)

A Phase I, first-in-human, open label, dose escalation study of MGD007, a humanized gpA33 × CD3 dual-affinity re-targeting (DART(®)) protein in patients with relapsed/refractory metastatic colorectal carcinoma
por: Hurwitz, Herbert, et al.
Publicado: (2014)

Flexible, rule-based dose escalation: The cohort-sequence design
por: Li, Shuang, et al.
Publicado: (2020)

A146 THE EFFECTIVENESS OF USTEKINUMAB DOSE ESCALATION IN PATIENTS WITH ULCERATIVE COLITIS
por: Albino, L, et al.
Publicado: (2022)

Phase Ib/II, open-label, dose-escalation study of LGX818, an oral selective BRAF inhibitor, in combination with MEK162, an oral MEK1/2 inhibitor, in patients with BRAF V600-dependent advanced solid tumors: preliminary results
por: Kefford, Richard, et al.
Publicado: (2014)

The 3+3 versus model-based approach: implementation in the CAPCISUM pancreatic cancer trial
por: Qian, Wendi, et al.
Publicado: (2015)

Thermal dose and radiation dose comparison based on cell survival
por: Lee, Meredith, et al.
Publicado: (2015)

Modelling health systems barriers to successful malaria management
por: Rao, Bhargavi, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_eighvmihp3eeecbos9qc3j8394