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HIV-1 Tat protein enhances the intracellular growth of Leishmania amazonensis via the ds-RNA induced protein PKR

HIV-1 co-infection with human parasitic diseases is a growing public health problem worldwide. Leishmania parasites infect and replicate inside macrophages, thereby subverting host signaling pathways, including the response mediated by PKR. The HIV-1 Tat protein interacts with PKR and plays a pivota...

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Detalles Bibliográficos
Autores principales: Vivarini, Áislan de Carvalho, Santos Pereira, Renata de Meirelles, Barreto-de-Souza, Victor, Temerozo, Jairo Ramos, Soares, Deivid C., Saraiva, Elvira M., Saliba, Alessandra Mattos, Bou-Habib, Dumith Chequer, Lopes, Ulisses Gazos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660360/
https://www.ncbi.nlm.nih.gov/pubmed/26608746
http://dx.doi.org/10.1038/srep16777