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A NEW POSSIBILITY FOR SURVEILLANCE: DO WE IDENTIFY ALL CASES OF LEPTOSPIROSIS?

Leptospirosis is a febrile disease with a typically underestimated global incidence, especially in regions where dengue is endemic. Therefore, it is difficult to accurately determine the number of leptospirosis cases in these areas, which contributes to significant under-reporting this disease. In t...

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Autores principales: FONTES, Raissa Matos, CAVALCANTI, Luciano Pamplona de Góes, OLIVEIRA, Augusto César Aragão, BEZERRA, Laiane Fernanda de Melo, GOMES, Almira Maria Monteiro, COLARES, Jeová Keny Baima, LIMA, Danielle Malta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto de Medicina Tropical 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660457/
https://www.ncbi.nlm.nih.gov/pubmed/26603235
http://dx.doi.org/10.1590/S0036-46652015000500014
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author FONTES, Raissa Matos
CAVALCANTI, Luciano Pamplona de Góes
OLIVEIRA, Augusto César Aragão
BEZERRA, Laiane Fernanda de Melo
GOMES, Almira Maria Monteiro
COLARES, Jeová Keny Baima
LIMA, Danielle Malta
author_facet FONTES, Raissa Matos
CAVALCANTI, Luciano Pamplona de Góes
OLIVEIRA, Augusto César Aragão
BEZERRA, Laiane Fernanda de Melo
GOMES, Almira Maria Monteiro
COLARES, Jeová Keny Baima
LIMA, Danielle Malta
author_sort FONTES, Raissa Matos
collection PubMed
description Leptospirosis is a febrile disease with a typically underestimated global incidence, especially in regions where dengue is endemic. Therefore, it is difficult to accurately determine the number of leptospirosis cases in these areas, which contributes to significant under-reporting this disease. In this study, we estimated the number of possible leptospirosis cases among dengue-like cases that were reported during 2008, 2010, and 2012 in the city of Fortaleza, northeast Brazil. Patients were evaluated for dengue and leptospirosis using immunoenzymatic tests for IgM antibodies that were specific to each pathogen. Among the suspected cases of dengue that resulted as negative in laboratory tests, 10.8% (2008), 19.2% (2010), and 30.8% (2012) were confirmed to be leptospirosis. Considering the cases reported by the surveillance authority as dengue that were subsequently discarded based on the laboratory test results, we estimate that the number of actual leptospirosis cases may be 26 to 49 times higher than those diagnosed and reported by the Health Services. Furthermore, we believe that approximately 20% of dengue-like cases may be leptospirosis cases in areas where the two diseases are endemic.
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spelling pubmed-46604572015-12-10 A NEW POSSIBILITY FOR SURVEILLANCE: DO WE IDENTIFY ALL CASES OF LEPTOSPIROSIS? FONTES, Raissa Matos CAVALCANTI, Luciano Pamplona de Góes OLIVEIRA, Augusto César Aragão BEZERRA, Laiane Fernanda de Melo GOMES, Almira Maria Monteiro COLARES, Jeová Keny Baima LIMA, Danielle Malta Rev Inst Med Trop Sao Paulo Brief Communication Leptospirosis is a febrile disease with a typically underestimated global incidence, especially in regions where dengue is endemic. Therefore, it is difficult to accurately determine the number of leptospirosis cases in these areas, which contributes to significant under-reporting this disease. In this study, we estimated the number of possible leptospirosis cases among dengue-like cases that were reported during 2008, 2010, and 2012 in the city of Fortaleza, northeast Brazil. Patients were evaluated for dengue and leptospirosis using immunoenzymatic tests for IgM antibodies that were specific to each pathogen. Among the suspected cases of dengue that resulted as negative in laboratory tests, 10.8% (2008), 19.2% (2010), and 30.8% (2012) were confirmed to be leptospirosis. Considering the cases reported by the surveillance authority as dengue that were subsequently discarded based on the laboratory test results, we estimate that the number of actual leptospirosis cases may be 26 to 49 times higher than those diagnosed and reported by the Health Services. Furthermore, we believe that approximately 20% of dengue-like cases may be leptospirosis cases in areas where the two diseases are endemic. Instituto de Medicina Tropical 2015 /pmc/articles/PMC4660457/ /pubmed/26603235 http://dx.doi.org/10.1590/S0036-46652015000500014 Text en http://creativecommons.org/licenses/by-nc/4.0 This is an open-access article distributed under the terms of the Creative Commons Attribution License
spellingShingle Brief Communication
FONTES, Raissa Matos
CAVALCANTI, Luciano Pamplona de Góes
OLIVEIRA, Augusto César Aragão
BEZERRA, Laiane Fernanda de Melo
GOMES, Almira Maria Monteiro
COLARES, Jeová Keny Baima
LIMA, Danielle Malta
A NEW POSSIBILITY FOR SURVEILLANCE: DO WE IDENTIFY ALL CASES OF LEPTOSPIROSIS?
title A NEW POSSIBILITY FOR SURVEILLANCE: DO WE IDENTIFY ALL CASES OF LEPTOSPIROSIS?
title_full A NEW POSSIBILITY FOR SURVEILLANCE: DO WE IDENTIFY ALL CASES OF LEPTOSPIROSIS?
title_fullStr A NEW POSSIBILITY FOR SURVEILLANCE: DO WE IDENTIFY ALL CASES OF LEPTOSPIROSIS?
title_full_unstemmed A NEW POSSIBILITY FOR SURVEILLANCE: DO WE IDENTIFY ALL CASES OF LEPTOSPIROSIS?
title_short A NEW POSSIBILITY FOR SURVEILLANCE: DO WE IDENTIFY ALL CASES OF LEPTOSPIROSIS?
title_sort new possibility for surveillance: do we identify all cases of leptospirosis?
topic Brief Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660457/
https://www.ncbi.nlm.nih.gov/pubmed/26603235
http://dx.doi.org/10.1590/S0036-46652015000500014
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