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A NEW POSSIBILITY FOR SURVEILLANCE: DO WE IDENTIFY ALL CASES OF LEPTOSPIROSIS?
Leptospirosis is a febrile disease with a typically underestimated global incidence, especially in regions where dengue is endemic. Therefore, it is difficult to accurately determine the number of leptospirosis cases in these areas, which contributes to significant under-reporting this disease. In t...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Instituto de Medicina Tropical
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660457/ https://www.ncbi.nlm.nih.gov/pubmed/26603235 http://dx.doi.org/10.1590/S0036-46652015000500014 |
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author | FONTES, Raissa Matos CAVALCANTI, Luciano Pamplona de Góes OLIVEIRA, Augusto César Aragão BEZERRA, Laiane Fernanda de Melo GOMES, Almira Maria Monteiro COLARES, Jeová Keny Baima LIMA, Danielle Malta |
author_facet | FONTES, Raissa Matos CAVALCANTI, Luciano Pamplona de Góes OLIVEIRA, Augusto César Aragão BEZERRA, Laiane Fernanda de Melo GOMES, Almira Maria Monteiro COLARES, Jeová Keny Baima LIMA, Danielle Malta |
author_sort | FONTES, Raissa Matos |
collection | PubMed |
description | Leptospirosis is a febrile disease with a typically underestimated global incidence, especially in regions where dengue is endemic. Therefore, it is difficult to accurately determine the number of leptospirosis cases in these areas, which contributes to significant under-reporting this disease. In this study, we estimated the number of possible leptospirosis cases among dengue-like cases that were reported during 2008, 2010, and 2012 in the city of Fortaleza, northeast Brazil. Patients were evaluated for dengue and leptospirosis using immunoenzymatic tests for IgM antibodies that were specific to each pathogen. Among the suspected cases of dengue that resulted as negative in laboratory tests, 10.8% (2008), 19.2% (2010), and 30.8% (2012) were confirmed to be leptospirosis. Considering the cases reported by the surveillance authority as dengue that were subsequently discarded based on the laboratory test results, we estimate that the number of actual leptospirosis cases may be 26 to 49 times higher than those diagnosed and reported by the Health Services. Furthermore, we believe that approximately 20% of dengue-like cases may be leptospirosis cases in areas where the two diseases are endemic. |
format | Online Article Text |
id | pubmed-4660457 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Instituto de Medicina Tropical |
record_format | MEDLINE/PubMed |
spelling | pubmed-46604572015-12-10 A NEW POSSIBILITY FOR SURVEILLANCE: DO WE IDENTIFY ALL CASES OF LEPTOSPIROSIS? FONTES, Raissa Matos CAVALCANTI, Luciano Pamplona de Góes OLIVEIRA, Augusto César Aragão BEZERRA, Laiane Fernanda de Melo GOMES, Almira Maria Monteiro COLARES, Jeová Keny Baima LIMA, Danielle Malta Rev Inst Med Trop Sao Paulo Brief Communication Leptospirosis is a febrile disease with a typically underestimated global incidence, especially in regions where dengue is endemic. Therefore, it is difficult to accurately determine the number of leptospirosis cases in these areas, which contributes to significant under-reporting this disease. In this study, we estimated the number of possible leptospirosis cases among dengue-like cases that were reported during 2008, 2010, and 2012 in the city of Fortaleza, northeast Brazil. Patients were evaluated for dengue and leptospirosis using immunoenzymatic tests for IgM antibodies that were specific to each pathogen. Among the suspected cases of dengue that resulted as negative in laboratory tests, 10.8% (2008), 19.2% (2010), and 30.8% (2012) were confirmed to be leptospirosis. Considering the cases reported by the surveillance authority as dengue that were subsequently discarded based on the laboratory test results, we estimate that the number of actual leptospirosis cases may be 26 to 49 times higher than those diagnosed and reported by the Health Services. Furthermore, we believe that approximately 20% of dengue-like cases may be leptospirosis cases in areas where the two diseases are endemic. Instituto de Medicina Tropical 2015 /pmc/articles/PMC4660457/ /pubmed/26603235 http://dx.doi.org/10.1590/S0036-46652015000500014 Text en http://creativecommons.org/licenses/by-nc/4.0 This is an open-access article distributed under the terms of the Creative Commons Attribution License |
spellingShingle | Brief Communication FONTES, Raissa Matos CAVALCANTI, Luciano Pamplona de Góes OLIVEIRA, Augusto César Aragão BEZERRA, Laiane Fernanda de Melo GOMES, Almira Maria Monteiro COLARES, Jeová Keny Baima LIMA, Danielle Malta A NEW POSSIBILITY FOR SURVEILLANCE: DO WE IDENTIFY ALL CASES OF LEPTOSPIROSIS? |
title | A NEW POSSIBILITY FOR SURVEILLANCE: DO WE IDENTIFY ALL CASES OF LEPTOSPIROSIS? |
title_full | A NEW POSSIBILITY FOR SURVEILLANCE: DO WE IDENTIFY ALL CASES OF LEPTOSPIROSIS? |
title_fullStr | A NEW POSSIBILITY FOR SURVEILLANCE: DO WE IDENTIFY ALL CASES OF LEPTOSPIROSIS? |
title_full_unstemmed | A NEW POSSIBILITY FOR SURVEILLANCE: DO WE IDENTIFY ALL CASES OF LEPTOSPIROSIS? |
title_short | A NEW POSSIBILITY FOR SURVEILLANCE: DO WE IDENTIFY ALL CASES OF LEPTOSPIROSIS? |
title_sort | new possibility for surveillance: do we identify all cases of leptospirosis? |
topic | Brief Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660457/ https://www.ncbi.nlm.nih.gov/pubmed/26603235 http://dx.doi.org/10.1590/S0036-46652015000500014 |
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