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Computational drug design strategies applied to the modelling of human immunodeficiency virus-1 reverse transcriptase inhibitors

Reverse transcriptase (RT) is a multifunctional enzyme in the human immunodeficiency virus (HIV)-1 life cycle and represents a primary target for drug discovery efforts against HIV-1 infection. Two classes of RT inhibitors, the nucleoside RT inhibitors (NRTIs) and the nonnucleoside transcriptase inh...

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Detalles Bibliográficos
Autores principales:	Santos, Lucianna Helene, Ferreira, Rafaela Salgado, Caffarena, Ernesto Raúl
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Instituto Oswaldo Cruz, Ministério da Saúde 2015
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660614/ https://www.ncbi.nlm.nih.gov/pubmed/26560977 http://dx.doi.org/10.1590/0074-02760150239

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