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Prion-like propagation of human brain-derived alpha-synuclein in transgenic mice expressing human wild-type alpha-synuclein

INTRODUCTION: Parkinson’s disease (PD) and multiple system atrophy (MSA) are neurodegenerative diseases that are characterized by the intracellular accumulation of alpha-synuclein containing aggregates. Recent increasing evidence suggests that Parkinson’s disease and MSA pathology spread throughout...

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Detalles Bibliográficos
Autores principales:	Bernis, Maria E., Babila, Julius T., Breid, Sara, Wüsten, Katharina Annick, Wüllner, Ullrich, Tamgüney, Gültekin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660655/ https://www.ncbi.nlm.nih.gov/pubmed/26612754 http://dx.doi.org/10.1186/s40478-015-0254-7

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