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TSG101, a tumor susceptibility gene, bidirectionally modulates cell invasion through regulating MMP-9 mRNA expression
BACKGROUND: Tumor susceptibility gene 101 (TSG101) was initially identified in fibroblasts as a tumor suppressor gene but subsequent studies show that TSG101 also functions as a tumor-enhancing gene in some epithelial tumor cells. Although previous studies have unraveled diverse biological functions...
Autores principales: | Sai, Xu Bin, Makiyama, Tomohiko, Sakane, Hiroshi, Horii, Yukimi, Hiraishi, Hideyuki, Shirataki, Hiromichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660656/ https://www.ncbi.nlm.nih.gov/pubmed/26608825 http://dx.doi.org/10.1186/s12885-015-1942-1 |
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